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Neuropsychiatric events and dolutegravir in HIV patients: a worldwide issue involving a class effect.

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We read with interest the work of Menard et al. [1] that brings additional knowledge on the neuropsychiatric tolerance of dolutegravir. They also provide pharmacokinetic data which is very welcomed… Click to show full abstract

We read with interest the work of Menard et al. [1] that brings additional knowledge on the neuropsychiatric tolerance of dolutegravir. They also provide pharmacokinetic data which is very welcomed as published works concerning the potential association between neuropsychiatric adverse drug reactions (ADRs) and dolutegravir concentrations are scarce. Their data are in line with other studies that recently reported neuropsychiatric adverse effects in patients receiving dolutegravir-containing regimen in other countries in Europe [2–4].

Keywords: events dolutegravir; worldwide issue; hiv patients; dolutegravir hiv; neuropsychiatric events; patients worldwide

Journal Title: AIDS
Year Published: 2017

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