Together with the increase in life expectancy of HIVinfected individuals with antiretroviral therapy (ART), morbidity and mortality from liver disease has sharply increased in individuals coinfected with hepatitis C or… Click to show full abstract
Together with the increase in life expectancy of HIVinfected individuals with antiretroviral therapy (ART), morbidity and mortality from liver disease has sharply increased in individuals coinfected with hepatitis C or B and exhibit advanced liver fibrosis and cirrhosis [1,2]. Since 2009, hepatocellular carcinoma (HCC) has emerged as a more common feature of end-stage liver disease in this population [3] and a recent retrospective multicohort analysis reported an increase in HCC by 11% per calendar year between 2001 and 2014, with an incidence of 1.6 [95% confidence interval (CI)1⁄4 1.3– 2.0] cases per 1000 person-years of follow-up [4].
               
Click one of the above tabs to view related content.