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A case of dolutegravir-induced cutaneous small vessel vasculitis.

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Cutaneous small vessel vasculitis (CSVV) is, by definition, a form of single organ vasculitis that is isolated to the skin without systemic involvement. It is often mediated by immune complex… Click to show full abstract

Cutaneous small vessel vasculitis (CSVV) is, by definition, a form of single organ vasculitis that is isolated to the skin without systemic involvement. It is often mediated by immune complex deposition in small vessels [1]. CSVV is usually a benign disease with a good clinical outcome, and is differentiated from the other cutaneous vasculitides by its lack of systemic effects [2]. However, it can frequently relapse, increasing healthcare costs and patient distress [3,4]. Our search of the literature revealed one other case report associating dolutegravir with the new onset of CSVV [5]. However, that case was confounded by a high HIV viral load. Thus, to our knowledge, a case in a well controlled patient with suppressed viral load has yet to be introduced.

Keywords: vessel vasculitis; cutaneous small; case; small vessel; vasculitis

Journal Title: AIDS
Year Published: 2019

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