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Contributing awareness of autoimmune hepatitis in HIV patients.

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Alterations in liver function tests (LFTs) are frequent in people living with HIV, being present in 21–32% of them. This alteration can be due to a chronic coinfection with hepatitis… Click to show full abstract

Alterations in liver function tests (LFTs) are frequent in people living with HIV, being present in 21–32% of them. This alteration can be due to a chronic coinfection with hepatitis B virus or hepatitis C virus (HCV), drug liver toxicity, neoplasms and, rarely, autoimmune diseases [1,2]. Autoimmune hepatitis (AIH) is a chronic, progressive hepatitis of unknown cause. The diagnosis is based on the histology, clinical manifestations, circulating autoantibodies and abnormal levels of serum globulins [3]. AIH has been rarely described in HIV-infected patients. Our review of the literature has identified 34 reported cases [4–20]. We contribute with seven cases from our cohort, the second largest series described in HIV-infected patients, and we also present a review of the literature.

Keywords: autoimmune hepatitis; awareness autoimmune; contributing awareness; hepatitis hiv; hepatitis

Journal Title: AIDS
Year Published: 2019

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