LAUSR

We read with interest the article by Strehlau et al. [1] on the diagnosis of two children infected with HIV in a recent issue of AIDS. On the basis of the findings that two breastfed children who showed positive results of nucleic acid amplification tests (NAAT) of HIV within 1 month after birth, became negative NAATand had no detectable viral load for several months, and finally turned out to be infected with HIV with definite evidence after weaning around 1 year of age, the authors hypothesized that breast milk from the mothers of these two children had HIVspecific or HIV-nonspecific factors that caused the undetectability of HIV in these two children until cessation of breastfeeding. However, we consider that the results should be cautiously interpreted, and that the persistent negativity of repeated HIV tests was possibly true and these two children were likely infected postnatally, because of the two following reasons.