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A 45-year-old man was found with multiple hepatic masses in CT/MR, suggesting liver metastases of unknown origin. F-FDG PET/CT showed several hypermetabolic masses in the liver; patchy increased uptake in… Click to show full abstract
A 45-year-old man was found with multiple hepatic masses in CT/MR, suggesting liver metastases of unknown origin. F-FDG PET/CT showed several hypermetabolic masses in the liver; patchy increased uptake in the pancreas; and FDG-avid lymph nodes in the neck, axilla, and mediastinum. Histopathology with biopsy revealed enriched IgG4-positive lymphoplasmacytic cells infiltrating in the liver, pancreas, and lymph nodes, which confirmed the diagnosis of IgG4-related disease. The lesions were diminished on follow-up PET/CT 3 months after treatment with prednisone. This case illustrated that multifocal FDG-avid hepatic mass might be the involvement of IgG4-related disease, which should be differentiated from malignancies.
Journal Title: Clinical Nuclear Medicine
Year Published: 2018
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