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Comparison of 18F-MFBG and 68Ga-DOTATATE PET/CT in the Imaging of Metastatic Paraganglioma and Pheochromocytoma.

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ABSTRACT Two men with metastatic paraganglioma/pheochromocytoma underwent PET/CT examination in our hospital to understand the treatment effect and progression of the disease. Both patients had previously been treated with 131I-MIBG,… Click to show full abstract

ABSTRACT Two men with metastatic paraganglioma/pheochromocytoma underwent PET/CT examination in our hospital to understand the treatment effect and progression of the disease. Both patients had previously been treated with 131I-MIBG, and at this evaluation, both of them underwent 68Ga-DOTATATE and 18F-MFBG PET/CT. The 68Ga-DOTATATE PET/CT showed more metastases in the images of these 2 patients. This case highlighted that 68Ga-DOTATATE PET/CT is superior to 18F-MFBG PET/CT in detecting metastases from paraganglioma and pheochromocytoma in these 2 patients.

Keywords: paraganglioma pheochromocytoma; 18f mfbg; pet; 68ga dotatate; dotatate pet

Journal Title: Clinical nuclear medicine
Year Published: 2022

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