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Epiglottic Polymorphous Adenocarcinoma With Multiple Bone Metastases Detected by 68Ga-FAPI PET/CT.

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ABSTRACT Polymorphous adenocarcinoma (PAC) is generally an indolent tumor that mostly commonly affects the minor salivary gland. Polymorphous adenocarcinoma with distant metastases is extremely rare. In this case, we reported… Click to show full abstract

ABSTRACT Polymorphous adenocarcinoma (PAC) is generally an indolent tumor that mostly commonly affects the minor salivary gland. Polymorphous adenocarcinoma with distant metastases is extremely rare. In this case, we reported 18F-FDG and 68Ga-FAPI PET/CT imaging findings in a rare case of epiglottic PAC with multiple bone metastases. 68Ga-FAPI PET/CT showed superiority over 18F-FDG PET/CT for detecting the primary and metastatic PAC. This case highlighted that 68Ga-FAPI may be a promising radiopharmaceutical in the diagnosis of PAC, especially for detecting the PACs arising in uncommon sites.

Keywords: fapi pet; fapi; 68ga fapi; polymorphous adenocarcinoma

Journal Title: Clinical nuclear medicine
Year Published: 2022

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