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ABSTRACT A 60-year-old man on methotrexate for treatment of adult-onset Still disease presented with acute onset of fever, pancytopenia, and deranged liver function. Besides FDG-avid lesions in spleen and skeleton,… Click to show full abstract
ABSTRACT A 60-year-old man on methotrexate for treatment of adult-onset Still disease presented with acute onset of fever, pancytopenia, and deranged liver function. Besides FDG-avid lesions in spleen and skeleton, his 18F-FDG PET/CT study showed diffuse and intense uptake in the liver with significantly suppressed heart and brain activity (reminiscent of a hepatic superscan). Subsequent biopsy confirmed the diagnosis of methotrexate-associated lymphoproliferative disorder.
Keywords:
methotrexate associated;
methotrexate;
hepatic superscan;
lymphoproliferative disorder;
associated lymphoproliferative
Journal Title: Clinical nuclear medicine
Year Published: 2023
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Journal Title: Clinical nuclear medicine
Year Published: 2023
Link to full text (if available)
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recommendations!