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68Ga-FAPI PET/MR for Active Thyroid Eye Disease Following Thyroidectomy: A Case Supporting Its Dual Role in Clinical Management.

A 30-year-old man experienced ocular motility impairment and exophthalmos immediately after a total thyroidectomy for papillary thyroid carcinoma at an external hospital. Two months later, 131I therapy exacerbated his ocular… Click to show full abstract

A 30-year-old man experienced ocular motility impairment and exophthalmos immediately after a total thyroidectomy for papillary thyroid carcinoma at an external hospital. Two months later, 131I therapy exacerbated his ocular symptoms. He presented to our ophthalmology department for evaluation, where a 68Ga-FAPI PET/MR scan revealed active thyroid eye disease (TED) and residual tumor lesions. Based on these findings and clinical evaluation, a multidisciplinary team formulated and implemented an effective treatment plan. This case highlights the dual role of 68Ga-FAPI PET/MR in assessing TED activity and postoperative tumor status, providing critical insights for managing TED in the context of recent thyroidectomy.

Keywords: fapi pet; thyroid eye; 68ga fapi; active thyroid

Journal Title: Clinical nuclear medicine
Year Published: 2025

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