LAUSR

S olid organ transplant recipients (SOTRs) are at risk for severe coronavirus disease 2019 (COVID-19) infection because of immunosuppressive medications and comorbidities. 1,2 When Omicron (B.1.1.529) became the dominant severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant, it was unclear what severity of illness this would cause in SOTRs, in comparison with previous variants. We collected data on the clinical outcomes of COVID-19 infection in SOTRs at a single center between December 22, 2021, and February 9, 2022, corresponding to the Omicron surge in our region, and compared these with earlier outcomes from our center in the pandemic. 3 To identify new cases of COVID-19, a daily report was generated from Epic, the electronic medical record (EMR) at Johns Hopkins, of any positive SARS-COV-2 polymerase chain reaction or antigen test result for a patient identified in the EMR as an SOTR. This report captured SARS-CoV-2 test results from the Johns Hopkins Health System, other centers, community hospitals, and outpatient clin-ics through Care Everywhere and Chesapeake Regional Information System for our Patients, the designated Health Information Exchange for the state of Maryland. With approval from