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Simultaneous Bilateral Serous Retinal Detachments and Cortical Visual Loss in the PRES HELLP Syndrome.

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P reeclampsia/eclampsia, posterior reversible encephalopathy syndrome (PRES), and the hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome are all complications of pregnancy which share some pathogenic features and risk… Click to show full abstract

P reeclampsia/eclampsia, posterior reversible encephalopathy syndrome (PRES), and the hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome are all complications of pregnancy which share some pathogenic features and risk factors. Both PRES and HELLP have been associated with visual loss. The underlying pathogenic mechanisms may be similar—breakdown of endothelial blood–brain in PRES or blood–retinal barrier in HELLP. The role of the coexistence of the 2 disorders (PRES/ HELLP) in the same patient may manifest with both anterior and posterior visual pathway disease in the form of serous retinal detachments (SRD) and cortical visual loss. We describe the shared and distinct pathogenic mechanisms for both PRES and HELLP and their significance to ophthalmologists. To the best of our knowledge, this is the first such case to be described in the English language, neuroophthalmic literature.

Keywords: pres hellp; visual loss; hellp syndrome; serous retinal; retinal detachments

Journal Title: Journal of Neuro-Ophthalmology
Year Published: 2020

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