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Mechanistic Insights into MicroRNA-Mediated Gene Silencing.

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MicroRNAs (miRNAs) posttranscriptionally regulate gene expression by repressing protein synthesis and exert a broad influence over development, physiology, adaptation, and disease. Over the past two decades, great strides have been… Click to show full abstract

MicroRNAs (miRNAs) posttranscriptionally regulate gene expression by repressing protein synthesis and exert a broad influence over development, physiology, adaptation, and disease. Over the past two decades, great strides have been made toward elucidating how miRNAs go about shutting down messenger RNA (mRNA) translation and promoting mRNA decay.

Keywords: mediated gene; gene silencing; gene; insights microrna; mechanistic insights; microrna mediated

Journal Title: Cold Spring Harbor perspectives in biology
Year Published: 2019

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