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Combining the power of Xenopus developmental biology with CRISPR-based technologies promises great discoveries in understanding and treating human genetic disorders. Here we provide a practical pipeline for how to go… Click to show full abstract
Combining the power of Xenopus developmental biology with CRISPR-based technologies promises great discoveries in understanding and treating human genetic disorders. Here we provide a practical pipeline for how to go from known disease gene(s) or risk gene(s) of interest to methods for gaining functional insight into the contribution of these genes to disorder etiology in humans.
Keywords:
disorders crispr;
crispr technologies;
modeling human;
human genetic;
technologies xenopus;
genetic disorders
Journal Title: Cold Spring Harbor protocols
Year Published: 2021
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Journal Title: Cold Spring Harbor protocols
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!