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Viscoelastically coupled excitable oscillators are used to model individually beating spatially separated cardiomyocytes surrounded by an extracellular matrix (ECM). We investigate how mechanical coupling via the ECM can synchronize two… Click to show full abstract
Viscoelastically coupled excitable oscillators are used to model individually beating spatially separated cardiomyocytes surrounded by an extracellular matrix (ECM). We investigate how mechanical coupling via the ECM can synchronize two such oscillators with excitation contraction coupling and electromechanical feedback and how this synchronization depends on the rheological properties of the ECM. Extending our study to a linear chain of coupled oscillators we find a transition to synchronization as the ECM becomes stiffer. In the case of purely elastic coupling we observe antiphase chimera states.
Journal Title: Physical Review E
Year Published: 2019
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