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The interpretation of cryo-EM density by atomic models remains a daunting task owing to the identification of appropriate threshold levels at low signal-to-noise ratios in high-resolution shells and weak structural… Click to show full abstract
The interpretation of cryo-EM density by atomic models remains a daunting task owing to the identification of appropriate threshold levels at low signal-to-noise ratios in high-resolution shells and weak structural features. It is shown that transforming cryo-EM densities to confidence maps followed by false discovery rate-based thresholding provides a robust way to interpret cryo-EM structures.
Keywords:
discovery rate;
false discovery;
cryo density
Journal Title: IUCrJ
Year Published: 2019
Link to full text (if available)
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Journal Title: IUCrJ
Year Published: 2019
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!