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Microbatch under-oil salt screening of organic cations: single-crystal growth of active pharmaceutical ingredients

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The under-oil crystallization method was successfully adopted for the crystallization of organic salts. Compared with the previously reported vapour-diffusion-based nano-crystallization technique, the under-oil method generated single crystals of more different… Click to show full abstract

The under-oil crystallization method was successfully adopted for the crystallization of organic salts. Compared with the previously reported vapour-diffusion-based nano-crystallization technique, the under-oil method generated single crystals of more different salts for all studied compounds.

Keywords: screening organic; microbatch oil; oil; salt screening; organic cations; oil salt

Journal Title: IUCrJ
Year Published: 2019

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