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Comparing serial X-ray crystallography and microcrystal electron diffraction (MicroED) as methods for routine structure determination from small macromolecular crystals

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Serial X-ray crystallography and microcrystal electron diffraction were performed using microcrystals of the enzyme cyclophilin A. The results highlight the strengths and weakness of the two complementary methods. Click to show full abstract

Serial X-ray crystallography and microcrystal electron diffraction were performed using microcrystals of the enzyme cyclophilin A. The results highlight the strengths and weakness of the two complementary methods.

Keywords: microcrystal electron; crystallography microcrystal; serial ray; ray crystallography; electron diffraction

Journal Title: IUCrJ
Year Published: 2020

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