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Organism-specific differences in the binding of ketoprofen to serum albumin

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Ketoprofen exhibits different binding-site preferences when interacting with mammalian albumins from different species. The drug-binding properties of albumins cannot easily be predicted based only on a complex of albumin from… Click to show full abstract

Ketoprofen exhibits different binding-site preferences when interacting with mammalian albumins from different species. The drug-binding properties of albumins cannot easily be predicted based only on a complex of albumin from another species even when the drug-binding sites exhibit a high degree of conservation between species.

Keywords: specific differences; binding ketoprofen; ketoprofen serum; organism specific; differences binding; albumin

Journal Title: IUCrJ
Year Published: 2022

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