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X-ray crystallography at variable temperature for SARS-CoV-2 Mpro reveals a complex conformational landscape, including a mobile metal at the catalytic dyad, mercurial conformational heterogeneity at various sites, and an intramolecular… Click to show full abstract
X-ray crystallography at variable temperature for SARS-CoV-2 Mpro reveals a complex conformational landscape, including a mobile metal at the catalytic dyad, mercurial conformational heterogeneity at various sites, and an intramolecular network bridging the active site and dimer interface.
Keywords:
temperature dependent;
ensemble sars;
temperature;
dependent conformational;
conformational ensemble;
sars cov
Journal Title: IUCrJ
Year Published: 2022
Link to full text (if available)
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Journal Title: IUCrJ
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!