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Synthesis and crystal structure of N-(4-chlorophenyl)-5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-2-amine

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The title compound, N-(4-chlorophenyl)-5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-2-amine, was synthesized by cyclization of 1-(4,6-dimethylpyrimidin-2-yl)-4-phenylthiosemicarbazide in the presence of Ni(NO3)2. In the crystal, molecules form inversion dimers via pairs of N—H⋯N hydrogen bonds, which are… Click to show full abstract

The title compound, N-(4-chlorophenyl)-5,7-dimethyl-1,2,4-triazolo[1,5-a]pyrimidin-2-amine, was synthesized by cyclization of 1-(4,6-dimethylpyrimidin-2-yl)-4-phenylthiosemicarbazide in the presence of Ni(NO3)2. In the crystal, molecules form inversion dimers via pairs of N—H⋯N hydrogen bonds, which are packed into layers by π-stacking interactions between the aromatic systems of neighbouring molecules.

Keywords: chlorophenyl dimethyl; pyrimidin amine; triazolo pyrimidin; dimethyl triazolo

Journal Title: Acta Crystallographica Section E: Crystallographic Communications
Year Published: 2017

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