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Crystal structure of 1,1′-{(1E,1′E)-[4,4′-(9H-fluorene-9,9-diyl)bis(4,1-phenylene)]bis(azanylylidene)bis(methanylylidene)}bis(naphthalen-2-ol) dichlorobenzene monosolvate

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A novel bis(anil) compound was synthesized and structurally characterized. Theoretical calculations suggested that the new bis(hydroxyimine) will exhibit histone deacetylase SIRT2, histone deacetylase class III and histone deacetylase SIRT1 activities,… Click to show full abstract

A novel bis(anil) compound was synthesized and structurally characterized. Theoretical calculations suggested that the new bis(hydroxyimine) will exhibit histone deacetylase SIRT2, histone deacetylase class III and histone deacetylase SIRT1 activities, and will act as inhibitor to aspulvinone dimethylallyltransferase, dehydro-l-gulonate decarboxylase and glutathione thiolesterase.

Keywords: crystal structure; diyl bis; fluorene diyl; histone deacetylase; structure fluorene; bis

Journal Title: Acta Crystallographica Section E: Crystallographic Communications
Year Published: 2020

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