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Calcium is a highly widespread and versatile intracellular ion that can control a wide range of temporal dynamics in the brain such as synaptic plasticity. This brief presents a novel… Click to show full abstract
Calcium is a highly widespread and versatile intracellular ion that can control a wide range of temporal dynamics in the brain such as synaptic plasticity. This brief presents a novel and efficient digital circuit for implementing a calcium-based plasticity model aimed at reproducing relevant biological dynamics. Accordingly, we investigate the feasibility of the proposed model in a minimal neural network stressing on the effect of calcium oscillations on synaptic plasticity with various neuronal stimulation protocols. MATLAB simulations and physical implementations on field-programmable gate array confirm that the proposed model, with considerably low hardware overhead, can fairly mimic the relevant biological dynamics.
Journal Title: IEEE Transactions on Circuits and Systems II: Express Briefs
Year Published: 2017
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