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A 460 800 Pixels CMOS Capacitive Sensor Array With Programmable Fusion Pixels and Noise Canceling for Life Science Applications
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Capacitive sensor array (CSA) plays an important role in life science applications, such as cell monitoring, DNA detection, or drug screening. This brief presents a $480\times 960$ time-sharing TDC (ts-TDC)… Click to show full abstract
Capacitive sensor array (CSA) plays an important role in life science applications, such as cell monitoring, DNA detection, or drug screening. This brief presents a $480\times 960$ time-sharing TDC (ts-TDC) architecture of global shutter CSA. It provides an opportunity to merge interfacing, read-out and sampling circuits in pixel and dynamically adjust the electrode size according to the characteristic of biosample. Each pixel size is within $2.25\times 2.25\,\,\mu m^{2}$ . The sensitivity of the proposed CSA is 6.896 codes/fF, and 43 fps can be adopted for real-time monitoring. Experiment results show that noise canceling significantly improves the sensing performance. Moreover, sensitivity can be optimized by given fusion-pixel pattern, making our proposal very flexible and suitable for cell biology applications and personalized medicine.
