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Viral shedding and the durability of IgG antibodies to SARS-CoV-2.

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We followed 45 participants in Surabaya, Indonesia, for 10 months and compared their polymerase chain reaction (PCR) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) results. Thirteen… Click to show full abstract

We followed 45 participants in Surabaya, Indonesia, for 10 months and compared their polymerase chain reaction (PCR) and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) results. Thirteen out of 45 participants were IgG seropositive at least once while the remaining 32 stayed IgG seronegative throughout the study. Among 13 seropositive participants, 9 participants were consecutively seropositive at least twice and were eligible for IgG longevity evaluation. The duration of IgG detection varied from 47 to ≥ 233 days. We observed intermittent re-positive PCR results suggestive of viral shedding in subjects with a longer duration of IgG detection. This article is protected by copyright. All rights reserved.

Keywords: igg antibodies; viral shedding; shedding durability; durability igg; igg; sars cov

Journal Title: Microbiology and immunology
Year Published: 2022

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