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Genetic variants in the histone methylation and acetylation pathway and their risks in eight types of cancers

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The histone methylation and acetylation pathway genes regulate cell growth and survival. Aberrations in this pathway are implicated in a variety of cancers. This study aimed to identify germline genetic… Click to show full abstract

The histone methylation and acetylation pathway genes regulate cell growth and survival. Aberrations in this pathway are implicated in a variety of cancers. This study aimed to identify germline genetic variants in histone methylation and acetylation pathway genes that may contribute to risk in eight types of cancers and to explore the relation between the whole pathway and their risks in these types of cancers.

Keywords: histone methylation; methylation acetylation; types cancers; acetylation pathway

Journal Title: Journal of Digestive Diseases
Year Published: 2018

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