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Several studies have shown that colchicine exhibits an improvement in the symptoms of knee osteoarthritis (OA) but its effect on disease progression is unknown. To clarify the mechanism of action… Click to show full abstract
Several studies have shown that colchicine exhibits an improvement in the symptoms of knee osteoarthritis (OA) but its effect on disease progression is unknown. To clarify the mechanism of action this study was done to see if colchicine prevents degradation of collagen fiber network in OA by studying serum cartilage oligomeric matrix protein (COMP) levels, a marker of cartilage turnover, over a period of 1 year.
Keywords:
fiber network;
degradation collagen;
collagen fiber
Journal Title: International Journal of Rheumatic Diseases
Year Published: 2018
Link to full text (if available)
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Journal Title: International Journal of Rheumatic Diseases
Year Published: 2018
Link to full text (if available)
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recommendations!