LAUSR

Dear Editor, Overlap syndrome (OS) is an uncommon rheumatological condition wherein there is an occurrence of two or more well-defined connective tissue diseases (CTDs) at the same or at different times in the same patient. While OS is most often described in association with systemic sclerosis, that involving idiopathic inflammatory myopathies (IIMs) are uncommon. Primary vasculitides were not encompassed in the above definition of OS until the publication of a few recent case reports. Antineutrophil cytoplasmic autoantibody (ANCA)-associated vasculitis (AAV) overlapped with IIM is even more rare. To the best of our knowledge, only two case reports of an overlap of AAV with dermatomyositis (DM) exist. There is a lack of such overlap cases in the children. We report a unique case of OS with juvenile DM and perinuclear (PR3)-ANCA vasculitis.