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Diagnostic utility of HLA‐B*5801 screening in severe allopurinol hypersensitivity syndrome: an updated systematic review and meta‐analysis

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Despite many studies suggesting an association between human leukocyte antigen (HLA)‐B*5801 and allopurinol‐induced toxic epidermal necrolysis (TEN) and Stevens‐Johnsons syndrome (SJS), the evidence of association in different populations and the… Click to show full abstract

Despite many studies suggesting an association between human leukocyte antigen (HLA)‐B*5801 and allopurinol‐induced toxic epidermal necrolysis (TEN) and Stevens‐Johnsons syndrome (SJS), the evidence of association in different populations and the degree of association remain uncertain.

Keywords: screening severe; hla; 5801 screening; diagnostic utility; utility hla; hla 5801

Journal Title: International Journal of Rheumatic Diseases
Year Published: 2017

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