Behçet's disease (BD) is a chronic systemic disorder characterized by inflammation of multiple organs, such as eyes, mucosa, skin, brain, joints, and vessels.1 Vascular manifestations, which consist of arterial involvements… Click to show full abstract
Behçet's disease (BD) is a chronic systemic disorder characterized by inflammation of multiple organs, such as eyes, mucosa, skin, brain, joints, and vessels.1 Vascular manifestations, which consist of arterial involvements and venous involvements, affect 15%-40% of patients with BD.2 Pulmonary involvements, including pulmonary thrombosis and pulmonary aneurysms, are less common, but associated with poor prognosis and severe cases and are most common among younger men.3 Anti-tumor necrosis factor (anti-TNF) inhibitors have been recommended for the treatment of severe cases of vascular BD.4 However, the use of TNF inhibitors has been reported to cause adverse effects such as infections, especially for older patients.5 Herein, we present a case of an older patient with BD, who developed refractory pulmonary artery thrombosis, improved with adalimumab (ADA), and sustained remission for 1 year without adverse effects.
               
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