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Baseline clinical features predicting macrophage activation syndrome in patients with systemic adult‐onset Still’s disease receiving interleukin‐6 inhibitor treatment

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Macrophage activation syndrome (MAS), a severe complication of systemic adult‐onset Still’s disease (AOSD), has been reported to occur during interleukin‐6 (IL‐6) inhibitor treatment. However, predictors for MAS development are unknown.… Click to show full abstract

Macrophage activation syndrome (MAS), a severe complication of systemic adult‐onset Still’s disease (AOSD), has been reported to occur during interleukin‐6 (IL‐6) inhibitor treatment. However, predictors for MAS development are unknown. Therefore, this study investigated predictive features for MAS development after starting IL‐6 inhibitor treatment in systemic AOSD patients.

Keywords: macrophage activation; inhibitor treatment; activation syndrome; inhibitor; systemic adult

Journal Title: International Journal of Rheumatic Diseases
Year Published: 2022

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