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Treatment of advanced lung cancer based on genomic profiling using liquid biopsy (plasma): A review of three cases

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Of the 80 solid tumor cases in which liquid biopsy (LB) was performed using Guardant360 in the PROFILE study, nine were lung cancer cases. Here, we review three cases in… Click to show full abstract

Of the 80 solid tumor cases in which liquid biopsy (LB) was performed using Guardant360 in the PROFILE study, nine were lung cancer cases. Here, we review three cases in which LB was useful in diagnosing ALK fusion‐positive lung cancer, selecting sequential ALK‐tyrosine kinase inhibitors, confirming uncommon EGFR mutations, and receiving biomarker‐compatible therapy.

Keywords: review three; liquid biopsy; three cases; lung cancer; cancer

Journal Title: Thoracic Cancer
Year Published: 2021

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