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A targeted siRNA‐loaded PDL1‐exosome and functional evaluation against lung cancer

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As an endocytic nanosicle involved in intercellular communication, an exosome can efficiently deliver drugs from one cell to another and deliver therapeutic short interfering RNA (siRNA) to target cells. This… Click to show full abstract

As an endocytic nanosicle involved in intercellular communication, an exosome can efficiently deliver drugs from one cell to another and deliver therapeutic short interfering RNA (siRNA) to target cells. This is conducive to gene therapy for cancers. In this study, an exosome was used as the siRNA‐loaded substrate to prepare a targeted siRNA‐loaded PD‐L1 exosome and evaluate its function against lung cancer.

Keywords: lung cancer; sirna loaded; targeted sirna; cancer targeted; cancer

Journal Title: Thoracic Cancer
Year Published: 2022

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