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Clinical significance of MYC family protein expression in surgically resected high‐grade neuroendocrine carcinoma of the lung

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MYC family genes including MYC, MYCN, and MYCL are amplified and overexpressed as oncogenic drivers in high‐grade neuroendocrine carcinoma of the lung (HGNEC), but little is known about their clinical… Click to show full abstract

MYC family genes including MYC, MYCN, and MYCL are amplified and overexpressed as oncogenic drivers in high‐grade neuroendocrine carcinoma of the lung (HGNEC), but little is known about their clinical significance. This study evaluated the prognostic impact of MYC family protein expression in patients with surgically resected HGNEC.

Keywords: myc family; grade neuroendocrine; high grade; family; neuroendocrine carcinoma; carcinoma lung

Journal Title: Thoracic Cancer
Year Published: 2023

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