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A case of eosinophilic bronchiolitis after the initiation of immune checkpoint inhibitor.

A 50-year-old Japanese woman with advanced breast cancer presented with productive cough and dyspnea while she was receiving a sixth cycle of chemotherapy including atezolizumab. Chest computed tomography revealed bronchiolitis… Click to show full abstract

A 50-year-old Japanese woman with advanced breast cancer presented with productive cough and dyspnea while she was receiving a sixth cycle of chemotherapy including atezolizumab. Chest computed tomography revealed bronchiolitis and transbronchial lung cryobiopsy revealed eosinophilic bronchiolitis. Corticosteroid therapy successfully resolved her symptoms. Eosinophilic bronchiolitis is a rare but important immune-related adverse event; herein, we discuss its diagnosis and possible pathophysiology.

Keywords: case eosinophilic; immune checkpoint; bronchiolitis initiation; initiation immune; bronchiolitis; eosinophilic bronchiolitis

Journal Title: Thoracic cancer
Year Published: 2023

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