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Post‐cardiac arrest level of free‐plasma DNA and DNA‐histone complexes

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Plasma DNA‐histone complexes and total free‐plasma DNA have the potential to quantify the ischaemia‐reperfusion damages occurring after cardiac arrest. Furthermore, DNA‐histone complexes may have the potential of being a target… Click to show full abstract

Plasma DNA‐histone complexes and total free‐plasma DNA have the potential to quantify the ischaemia‐reperfusion damages occurring after cardiac arrest. Furthermore, DNA‐histone complexes may have the potential of being a target for future treatment. The aim was to examine if plasma DNA‐histone complexes and the levels of total free‐plasma DNA were elevated in post‐cardiac arrest patients compared with healthy individuals, and to examine if these biomarkers were capable of predicting mortality.

Keywords: histone complexes; plasma dna; dna histone; dna

Journal Title: Acta Anaesthesiologica Scandinavica
Year Published: 2017

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