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Impact of age on cardiovascular function, inflammation, and oxidative stress in experimental asphyxial cardiac arrest

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Advanced age is an independent predictor of poor outcome after cardiac arrest (CA). From experimental studies of regional ischemia‐reperfusion injury, advanced age is associated with larger infarct size, reduced organ… Click to show full abstract

Advanced age is an independent predictor of poor outcome after cardiac arrest (CA). From experimental studies of regional ischemia‐reperfusion injury, advanced age is associated with larger infarct size, reduced organ function, and augmented oxidative stress. The objective of this study was to investigate the effect of age on cardiovascular function, oxidative stress, inflammation, and endothelial activation after CA representing global ischemia‐reperfusion.

Keywords: age; age cardiovascular; cardiac arrest; function; oxidative stress

Journal Title: Acta Anaesthesiologica Scandinavica
Year Published: 2018

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