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Changes in vitamin D metabolites at the time of critical illness and 6 months later—A prospective observational study

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Despite multiple studies suggesting that low 25(OH)D‐vitamin levels are associated with worse outcomes in critically ill individuals, attempts to mitigate the outcomes by fixed dose enteral supplementation unguided by baseline… Click to show full abstract

Despite multiple studies suggesting that low 25(OH)D‐vitamin levels are associated with worse outcomes in critically ill individuals, attempts to mitigate the outcomes by fixed dose enteral supplementation unguided by baseline or target blood levels have been unsuccessful. Since a single measurement of 25(OH)D may not optimally reflect an individual's vitamin D status, we studied the plasma concentration of different vitamin D metabolites and their recovery during and following resolution of acute critical illness.

Keywords: changes vitamin; time critical; metabolites time; vitamin metabolites; critical illness

Journal Title: Acta Anaesthesiologica Scandinavica
Year Published: 2022

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