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A randomized controlled trial of oxycodone/acetaminophen versus acetaminophen alone for emergency department patients with musculoskeletal pain refractory to ibuprofen

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Use of oral opioids does not result in more pain relief than nonopioid alternatives when administered to patients as first‐line treatment for acute musculoskeletal pain. This study compared the efficacy… Click to show full abstract

Use of oral opioids does not result in more pain relief than nonopioid alternatives when administered to patients as first‐line treatment for acute musculoskeletal pain. This study compared the efficacy of oxycodone/acetaminophen to that of acetaminophen alone as second‐line treatment for patients with acute musculoskeletal pain who were administered prescription‐strength ibuprofen and reported insufficient relief 1 h later.

Keywords: acetaminophen alone; musculoskeletal pain; oxycodone acetaminophen; ibuprofen

Journal Title: Academic Emergency Medicine
Year Published: 2021

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