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Severity, course trajectory, and within‐person variability of individual symptoms in patients with major depressive disorder

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Depression shows a large heterogeneity of symptoms between and within persons over time. However, most outcome studies have assessed depression as a single underlying latent construct, using the sum score… Click to show full abstract

Depression shows a large heterogeneity of symptoms between and within persons over time. However, most outcome studies have assessed depression as a single underlying latent construct, using the sum score on psychometric scales as an indicator for severity. This study assesses longitudinal symptom‐specific trajectories and within‐person variability of major depressive disorder over a 9‐year period.

Keywords: depressive disorder; major depressive; within person; person variability; severity

Journal Title: Acta Psychiatrica Scandinavica
Year Published: 2019

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