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Metformin for the prevention of clozapine‐induced weight gain: A retrospective naturalistic cohort study

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Clozapine is presently the sole antipsychotic with an indication for treatment‐resistant Schizophrenia, but is associated with significant weight gain and other metabolic aberrations. This retrospective chart review aimed to evaluate… Click to show full abstract

Clozapine is presently the sole antipsychotic with an indication for treatment‐resistant Schizophrenia, but is associated with significant weight gain and other metabolic aberrations. This retrospective chart review aimed to evaluate the effectiveness of adjunctive metformin in preventing clozapine‐induced weight gain.

Keywords: induced weight; clozapine induced; weight gain; clozapine; metformin

Journal Title: Acta Psychiatrica Scandinavica
Year Published: 2022

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