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Identification and characterization of miRNAs during early pregnancy in domestic sheep

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Summary MicroRNA resources in sheep are limited compared with those in other domesticated mammalian species. By sequencing small RNAs of sheep corpus luteum and endometrium, we have generated the largest… Click to show full abstract

Summary MicroRNA resources in sheep are limited compared with those in other domesticated mammalian species. By sequencing small RNAs of sheep corpus luteum and endometrium, we have generated the largest amount of miRNA‐seq data and compiled the most comprehensive list thus far of miRNAs (n = 599) in sheep. Additionally, we observed a highly conserved maternally imprinted cluster of miRNAs on chromosome 18 homologous to that found on chromosome 14 in human and several other eutherian mammals.

Keywords: mirnas early; pregnancy domestic; domestic sheep; early pregnancy; characterization mirnas; identification characterization

Journal Title: Animal Genetics
Year Published: 2020

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