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Subacute cutaneous lupus erythematosus induced by nivolumab

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The dermoscopy of the HAS area in our patient (Fig. 1a) showed features consistent with previous reports, as well as previously undescribed glomerular vessels. Pigmented globules annularly surrounded by scales,… Click to show full abstract

The dermoscopy of the HAS area in our patient (Fig. 1a) showed features consistent with previous reports, as well as previously undescribed glomerular vessels. Pigmented globules annularly surrounded by scales, first described in HAS by Shiiya and colleagues, allowed this patient’s lesion to be distinguished from clinically and dermoscopically similar viral warts, seborrhoeic keratosis and Bowen’s disease. However this case of HAS lacked previously described white globules and did not have any of the melanoma-like dermoscopic features sometimes seen in HAS, such as streaks, blotches, regression structures, a blue-whitish veil and globule-like structures. The dermoscopic features of eccrine porocarcinoma (EPC) comprise polymorphous vessels, white-to-pink halos and pinkish-white structureless areas, which distinguish it from clinically similar poroma, melanoma, basal cell carcinoma and granuloma pyogenicum. There are no significant differences between the dermoscopic features of our pigmented APC and previously reported eccrine porocarcinoma except the presence of a grey hue, caused by the underlying dermatopathological pigmentation (Fig. 1b). Dermoscopy is useful in the diagnosis of HAS and APC and in discrimination between each of these two conditions and its respective clinical simulators.

Keywords: erythematosus induced; lupus erythematosus; subacute cutaneous; dermoscopic features; induced nivolumab; cutaneous lupus

Journal Title: Australasian Journal of Dermatology
Year Published: 2018

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