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A case of cutaneous extranodal natural killer/T‐cell lymphoma clinically and histopathologically mimicking interface dermatitis

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Extranodal natural killer/T‐cell lymphoma (ENKTL) is a rare but aggressive cancer characterised by angiocentric and angiodestructive infiltration by NK‐cells, or cytotoxic T‐cell types. Histopathologically, ENKTL shows a multinodular or diffuse… Click to show full abstract

Extranodal natural killer/T‐cell lymphoma (ENKTL) is a rare but aggressive cancer characterised by angiocentric and angiodestructive infiltration by NK‐cells, or cytotoxic T‐cell types. Histopathologically, ENKTL shows a multinodular or diffuse infiltration localised to vascular structures, resulting in angiodestruction and necrosis. We present a patient with an initially suspected diagnosis of benign interface dermatitis with a differential diagnosis of mycosis fungoides that was later found to be an aggressive extranodal natural killer/T‐cell lymphoma of a nasal type and with a dismal prognosis.

Keywords: killer cell; natural killer; extranodal natural; cell; cell lymphoma

Journal Title: Australasian Journal of Dermatology
Year Published: 2020

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