LAUSR

Turner syndrome is a chromosomal abnormality caused by the absence or abnormality of the X chromosome. Turner syndrome is often associated with autoimmune skin disease including alopecia areata (AA). Moreover, psoriasis associated with Turner syndrome has also been reported. However, coexistence of AA and psoriasis is rarely reported. We report a case of psoriasis vulgaris and AA associated with Turner syndrome. A 58-year-old woman with Turner syndrome presented with a more than ten-year history of alopecia totalis, refractory to treatment including squaric acid dibutylester. Additionally, she had a background of Hashimoto’s thyroiditis on levothyroxine. On examination of the scalp, only a single hair was detected (Fig. 1a,b). Scalp punch biopsy showed lymphocytic inflammation around the hair follicle (Fig. 1c). General skin examination revealed scaly erythematous plaques on her extremities (Fig. 1d,e). Biopsy from the right knee revealed confluent parakeratosis, absent granular layers and acanthosis with clubshaped rete ridges of even length (Fig. 1f). Based on these findings, the patient was diagnosed with psoriasis vulgaris