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Grouped follicular secondary syphilis: Case report and review of literature

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Secondary syphilis typically presents with macular, maculopapular or papular lesions, sometimes with systemic symptoms; however, there are some less common cutaneous presentations which can result in several differential diagnoses. We… Click to show full abstract

Secondary syphilis typically presents with macular, maculopapular or papular lesions, sometimes with systemic symptoms; however, there are some less common cutaneous presentations which can result in several differential diagnoses. We report the case of a 25‐year‐old man with the recent onset of a symmetric eruption of grouped follicular papules, for which syphilis was not originally considered. Histopathology revealed non‐caseating granulomas with a lichenoid infiltrate. Subsequent spirochete immunostaining was positive, and further physical examination revealed moth‐eaten alopecia, confirming the diagnosis of secondary syphilis.

Keywords: report; case; secondary syphilis; grouped follicular; follicular secondary; syphilis

Journal Title: Australasian Journal of Dermatology
Year Published: 2023

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