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Multiple primary melanomas: Is there a correlation between dermoscopic features and germline mutations?

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% of MPMs. 8 Colombino et al. reported a higher concordance rate (66.7%) but limited to only 12 patients. In our study, the concordance rate was 55.7%, consistently with previous… Click to show full abstract

% of MPMs. 8 Colombino et al. reported a higher concordance rate (66.7%) but limited to only 12 patients. In our study, the concordance rate was 55.7%, consistently with previous studies. 9 This was higher in males (61.5%) than in females (38.5%). One of the main aims of CM follow- up programs is to ensure a prompt detection and excision of atypical lesions. CM subjects may show a considerable number of nevi, often in a multiple dysplastic nevus syndrome. Considering that more than half of MPMs patients show a concordance between dermoscopic patterns, we believe that knowing the dermoscopic features of the first diagnosed CM may help the clinicians in the evaluation and decisional process of doubtful lesions. Though the germline mutational status does not appear to be correlated with a concordance in MPM dermoscopic presentation, but further studies are warranted

Keywords: primary melanomas; correlation dermoscopic; dermoscopic; multiple primary; dermoscopic features; melanomas correlation

Journal Title: Australasian Journal of Dermatology
Year Published: 2023

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