LAUSR

Androgenetic alopecia (AGA) is a disorder of miniaturization of hair follicle. The various treatment modalities approved in AGA include topical minoxidil, oral finasteride and hair transplantation.1 Amongst the newer modalities, autologous regenerative technologies including micrografts enriched with human follicle mesenchymal stem cells and platelet rich plasma (PRP) have been found to be beneficial in the management of AGA.2,3 Additionally, microneedling and lowlevel laser/light therapy have been found to promote hair regrowth.4 PRP is a preparation of plasma which is rich in growth factors and concentrated platelets. There is no standard technique of preparation, activation and administration of PRP. It can be prepared by double spin (DS) or single spin (SS) method. Calcium, thrombin and rarely low temperature have been used to activate it before injection.5 We sought to compare PRP prepared by DS and calcium activation (DS/CaPRP) and PRP prepared by SS and low temperature activation (SS/ LTPRP) in terms of efficacy, safety and simplicity in this prospective split scalp study.