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An investigation of the relationship between recurrent spontaneous abortion and memory T follicular helper cells

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Immune tolerance with respect to a semi‐allogeneic fetus plays a key role in the establishment of a pregnancy. Memory T follicular helper (Tfh) cells have a central role in the… Click to show full abstract

Immune tolerance with respect to a semi‐allogeneic fetus plays a key role in the establishment of a pregnancy. Memory T follicular helper (Tfh) cells have a central role in the regulation of the adaptive immune response. Much of our knowledge of memory Tfh cells’ function comes from immune‐related diseases. However, the true physiological characteristics of memory Tfh cells and their mode of action in pregnancy remain unclear.

Keywords: memory follicular; investigation relationship; tfh cells; follicular helper; memory

Journal Title: American Journal of Reproductive Immunology
Year Published: 2017

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