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Preeclampsia (PE) is associated with inflammation and decreased Treg cells and IL‐10. The reduced uterine perfusion pressure (RUPP) rat model of PE exhibits these characteristics, and we hypothesized that induction… Click to show full abstract
Preeclampsia (PE) is associated with inflammation and decreased Treg cells and IL‐10. The reduced uterine perfusion pressure (RUPP) rat model of PE exhibits these characteristics, and we hypothesized that induction of endogenous Tregs by a specific stimulus (CD28 superagonistic monoclonal antibody) would reduce inflammation, vasoactive factors, and hypertension in RUPP rats.
Keywords:
improve pathophysiology;
cells improve;
proliferation endogenous;
regulatory cells;
endogenous regulatory;
pathophysiology associated
Journal Title: American Journal of Reproductive Immunology
Year Published: 2017
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Journal Title: American Journal of Reproductive Immunology
Year Published: 2017
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!